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Complement Properdin Determines Disease Activity in MRL/lpr Mice
Background and objects: In systemic lupus erythematosus, circulating immune complexes activate complement and, when trapped in renal capillaries, cause glomerulonephritis. Mouse models have been used in the preclinical assessment of targeting complement activation pathways to manage chronic inflamma...
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| Udgivet i: | Medicina (Kaunas) |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7559332/ https://ncbi.nlm.nih.gov/pubmed/32867176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina56090430 |
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