Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the potential to reflect past interactions between genetic and environmental factors during early development and influence future health o...

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Udgivet i:Genome Med
Main Authors: Mordaunt, Charles E., Jianu, Julia M., Laufer, Benjamin I., Zhu, Yihui, Hwang, Hyeyeon, Dunaway, Keith W., Bakulski, Kelly M., Feinberg, Jason I., Volk, Heather E., Lyall, Kristen, Croen, Lisa A., Newschaffer, Craig J., Ozonoff, Sally, Hertz-Picciotto, Irva, Fallin, M. Daniele, Schmidt, Rebecca J., LaSalle, Janine M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559201/
https://ncbi.nlm.nih.gov/pubmed/33054850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00785-8
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