Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the potential to reflect past interactions between genetic and environmental factors during early development and influence future health o...

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Pubblicato in:Genome Med
Autori principali: Mordaunt, Charles E., Jianu, Julia M., Laufer, Benjamin I., Zhu, Yihui, Hwang, Hyeyeon, Dunaway, Keith W., Bakulski, Kelly M., Feinberg, Jason I., Volk, Heather E., Lyall, Kristen, Croen, Lisa A., Newschaffer, Craig J., Ozonoff, Sally, Hertz-Picciotto, Irva, Fallin, M. Daniele, Schmidt, Rebecca J., LaSalle, Janine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559201/
https://ncbi.nlm.nih.gov/pubmed/33054850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00785-8
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