Clonal tracing reveals diverse patterns of response to immune checkpoint blockade

BACKGROUND: Immune checkpoint blockade (ICB) therapy has improved patient survival in a variety of cancers, but only a minority of cancer patients respond. Multiple studies have sought to identify general biomarkers of ICB response, but elucidating the molecular and cellular drivers of resistance fo...

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Bibliografiset tiedot
Julkaisussa:Genome Biol
Päätekijät: Gu, Shengqing Stan, Wang, Xiaoqing, Hu, Xihao, Jiang, Peng, Li, Ziyi, Traugh, Nicole, Bu, Xia, Tang, Qin, Wang, Chenfei, Zeng, Zexian, Fu, Jingxin, Meyer, Cliff, Zhang, Yi, Cejas, Paloma, Lim, Klothilda, Wang, Jin, Zhang, Wubing, Tokheim, Collin, Sahu, Avinash Das, Xing, Xiaofang, Kroger, Benjamin, Ouyang, Zhangyi, Long, Henry, Freeman, Gordon J., Brown, Myles, Liu, X. Shirley
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559192/
https://ncbi.nlm.nih.gov/pubmed/33059736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02166-1
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