Curcumin Diglutaric Acid, a Prodrug of Curcumin Reduces Pain Hypersensitivity in Chronic Constriction Injury of Sciatic Nerve Induced-Neuropathy in Mice

The drug treatment for neuropathic pain remains a challenge due to poor efficacy and patient satisfaction. Curcumin has been reported to alleviate neuropathic pain, but its clinical application is hindered by its low solubility and poor oral bioavailability. Curcumin diglutaric acid (CurDG) is a cur...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Limcharoen, Thanchanok, Dasuni Wasana, Peththa Wadu, , Hasriadi, Muangnoi, Chawanphat, Vajragupta, Opa, Rojsitthisak, Pornchai, Towiwat, Pasarapa
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558758/
https://ncbi.nlm.nih.gov/pubmed/32867013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090212
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