Curcumin Diglutaric Acid, a Prodrug of Curcumin Reduces Pain Hypersensitivity in Chronic Constriction Injury of Sciatic Nerve Induced-Neuropathy in Mice

The drug treatment for neuropathic pain remains a challenge due to poor efficacy and patient satisfaction. Curcumin has been reported to alleviate neuropathic pain, but its clinical application is hindered by its low solubility and poor oral bioavailability. Curcumin diglutaric acid (CurDG) is a cur...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thanchanok Limcharoen, Peththa Wadu Dasuni Wasana, Hasriadi, Chawanphat Muangnoi, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2020-08-01
Cyfres:Pharmaceuticals
Pynciau:
neuropathic pain
chronic constriction injury
curcumin diglutaric acid
mechanical allodynia
thermal hyperalgesia
Mynediad Ar-lein:https://www.mdpi.com/1424-8247/13/9/212
Tagiau: Ychwanegu Tag
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