Curcumin Diglutaric Acid, a Prodrug of Curcumin Reduces Pain Hypersensitivity in Chronic Constriction Injury of Sciatic Nerve Induced-Neuropathy in Mice

The drug treatment for neuropathic pain remains a challenge due to poor efficacy and patient satisfaction. Curcumin has been reported to alleviate neuropathic pain, but its clinical application is hindered by its low solubility and poor oral bioavailability. Curcumin diglutaric acid (CurDG) is a cur...

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Detalhes bibliográficos
Main Authors: Thanchanok Limcharoen, Peththa Wadu Dasuni Wasana, Hasriadi, Chawanphat Muangnoi, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:Pharmaceuticals
Assuntos:
neuropathic pain
chronic constriction injury
curcumin diglutaric acid
mechanical allodynia
thermal hyperalgesia
Acesso em linha:https://www.mdpi.com/1424-8247/13/9/212
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