Systemic antitumor immunity by PD-1/PD-L1 inhibition is potentiated by vascular-targeted photodynamic therapy of primary tumors

PURPOSE: PD-1/PD-L1 pathway inhibition is effective against advanced renal cell carcinoma, although results are variable and may depend on host factors including the tumor microenvironment. Vascular-targeted photodynamic (VTP) therapy with the photosensitizer WST11 induces a defined local immune res...

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Publicat a:Clin Cancer Res
Autors principals: O’Shaughnessy, Matthew J., Murray, Katie S., La Rosa, Stephen P., Budhu, Sadna, Merghoub, Taha, Somma, Alexander, Monette, Sebastien, Kim, Kwanghee, Corradi, Renato Beluco, Scherz, Avigdor, Coleman, Jonathan A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558370/
https://ncbi.nlm.nih.gov/pubmed/28954788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0186
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