Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease

Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tangles are prime features of Alzheimer’s disease (AD). The pathology of AD is very complex and still not fully understood, since different neural cell types are involved in the disease. Although neuronal function is c...

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Spremljeno u:
Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Garcia-Leon, Juan Antonio, Caceres-Palomo, Laura, Sanchez-Mejias, Elisabeth, Mejias-Ortega, Marina, Nuñez-Diaz, Cristina, Fernandez-Valenzuela, Juan Jose, Sanchez-Varo, Raquel, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558359/
https://ncbi.nlm.nih.gov/pubmed/32962164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186867
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