Significance of druggable targets (PD-L1, KRAS, BRAF, PIK3CA, MSI, and HPV) on curatively resected esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, is involved in the pathogenesis of ESCC and thus is a potential therapeutic target. PIK3CA, KRAS, and BRAF m...

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Опубликовано в: :Diagn Pathol
Главные авторы: Lee, Hong Kyu, Kwon, Mi Jung, Ra, Yong Joon, Lee, Hee Sung, Kim, Hyoung Soo, Nam, Eun Sook, Cho, Seong Jin, Park, Hye-Rim, Min, Soo Kee, Seo, Jinwon, Choe, Ji-Young, Min, Kyueng-Whan, Kang, So Young
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557072/
https://ncbi.nlm.nih.gov/pubmed/33054840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-020-01045-4
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