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A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast

Cellular aging is a multifactorial process that is characterized by a decline in homeostatic capacity, best described at the molecular level. Physicochemical properties such as pH and macromolecular crowding are essential to all molecular processes in cells and require maintenance. Whether a drift i...

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Pubblicato in:eLife
Autori principali: Mouton, Sara N, Thaller, David J, Crane, Matthew M, Rempel, Irina L, Terpstra, Owen T, Steen, Anton, Kaeberlein, Matt, Lusk, C Patrick, Boersma, Arnold J, Veenhoff, Liesbeth M
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556870/
https://ncbi.nlm.nih.gov/pubmed/32990592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54707
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