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Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma

Cancer testis antigens (CTAs) are proteins whose expression is normally restricted to the testis but anomalously activated in human cancer. In sperm, a number of CTAs support energy generation, however, whether they contribute to tumor metabolism is not understood. We describe human COX6B2, a compon...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Cheng, Chun-Chun, Wooten, Joshua, Gibbs, Zane A, McGlynn, Kathleen, Mishra, Prashant, Whitehurst, Angelique W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
https://ncbi.nlm.nih.gov/pubmed/32990599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58108
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