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Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma

Cancer testis antigens (CTAs) are proteins whose expression is normally restricted to the testis but anomalously activated in human cancer. In sperm, a number of CTAs support energy generation, however, whether they contribute to tumor metabolism is not understood. We describe human COX6B2, a compon...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Cheng, Chun-Chun, Wooten, Joshua, Gibbs, Zane A, McGlynn, Kathleen, Mishra, Prashant, Whitehurst, Angelique W
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
https://ncbi.nlm.nih.gov/pubmed/32990599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58108
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