Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

ATP is essential for all living cells. However, how dead cells lose ATP has not been well investigated. In this study, we developed new FRET biosensors for dual imaging of intracellular ATP level and caspase-3 activity in single apoptotic cultured human cells. We show that the cytosolic ATP level st...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Imamura, Hiromi, Sakamoto, Shuichiro, Yoshida, Tomoki, Matsui, Yusuke, Penuela, Silvia, Laird, Dale W, Mizukami, Shin, Kikuchi, Kazuya, Kakizuka, Akira
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556867/
https://ncbi.nlm.nih.gov/pubmed/33052098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61960
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