Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

ATP is essential for all living cells. However, how dead cells lose ATP has not been well investigated. In this study, we developed new FRET biosensors for dual imaging of intracellular ATP level and caspase-3 activity in single apoptotic cultured human cells. We show that the cytosolic ATP level st...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Imamura, Hiromi, Sakamoto, Shuichiro, Yoshida, Tomoki, Matsui, Yusuke, Penuela, Silvia, Laird, Dale W, Mizukami, Shin, Kikuchi, Kazuya, Kakizuka, Akira
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556867/
https://ncbi.nlm.nih.gov/pubmed/33052098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61960
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