Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

ATP is essential for all living cells. However, how dead cells lose ATP has not been well investigated. In this study, we developed new FRET biosensors for dual imaging of intracellular ATP level and caspase-3 activity in single apoptotic cultured human cells. We show that the cytosolic ATP level st...

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Vydáno v:eLife
Hlavní autoři: Imamura, Hiromi, Sakamoto, Shuichiro, Yoshida, Tomoki, Matsui, Yusuke, Penuela, Silvia, Laird, Dale W, Mizukami, Shin, Kikuchi, Kazuya, Kakizuka, Akira
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556867/
https://ncbi.nlm.nih.gov/pubmed/33052098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61960
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