Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity

Xenograft models are invaluable tools in establishing the current paradigms of hematopoiesis and leukemogenesis. The zebrafish has emerged as a robust alternative xenograft model but, like mice, lacks specific cytokines that mimic the microenvironment found in human patients. To address this critica...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Haematologica
Main Authors: Rajan, Vinothkumar, Melong, Nicole, Wong, Wing Hing, King, Benjamin, Tong, R. Spencer, Mahajan, Nitin, Gaston, Daniel, Lund, Troy, Rittenberg, David, Dellaire, Graham, Campbell, Clinton J.V., Druley, Todd, Berman, Jason N.
Format: Artigo
Jezik:Inglês
Izdano: Fondazione Ferrata Storti 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556680/
https://ncbi.nlm.nih.gov/pubmed/33054079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.223040
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