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Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia

The zebrafish has become a popular human tumour xenograft model, particularly for solid tumours including prostate cancer (PCa). To date PCa xenotransplantation studies in zebrafish have not been performed in the presence of testosterone, even when employing androgen-dependent cell models, such as t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Melong, Nicole, Steele, Shelby, MacDonald, Morgan, Holly, Alice, Collins, Colin C., Zoubeidi, Amina, Berman, Jason N., Dellaire, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665934/
https://ncbi.nlm.nih.gov/pubmed/29089623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14413-w
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