Whole-genome sequencing reveals potent therapeutic strategy for monomorphic epitheliotropic intestinal T-cell lymphoma

Whole genomic and transcriptomic analyses of MEITL revealed multiple potential therapeutic targets. Synergistic effects of pimozide and romidepsin are shown in a well-characterized MEITL PDX model.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: Huang, Dachuan, Lim, Jing Quan, Cheah, Daryl Ming Zhe, Kahliab, Khalilatul Hanisah Binte Mohd, Laurensia, Yurike, Pang, Jane Wan Lu, Wong, Esther Kam Yin, Chia, Burton Kuan Hui, Goh, Jasmine, Zhang, Xiyun, Chan, Jason Yongsheng, Chow, Edward Kai-Hua, Tan, Soo Yong, Lim, Soon Thye, Ong, Choon Kiat
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2020
Pynciau:
Stimulus Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556141/
https://ncbi.nlm.nih.gov/pubmed/33017466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001782
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