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Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance

The activation of the Notch pathway induces glioblastoma (GBM) development. Since KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2) is involved in the Notch pathway, the detailed mechanism is still undetermined. The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases revealed that...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Tsai, Yu-Ling, Chang, Hsin-Han, Chen, Ying-Chuan, Chang, Yu-Chan, Chen, Ying, Tsai, Wen-Chiuan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555920/
https://ncbi.nlm.nih.gov/pubmed/32927743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8090339
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