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Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core–shell system for drug delivery

A drug encapsulation/delivery system using a novel principle is described that is based on an intra-particle migration of calcium ions between a central Ca(2+)-enriched nanoparticle core and the surrounding shell compartment. The supply of Ca(2+) is needed for the formation of a coacervate shell aro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Müller, Werner E. G., Tolba, Emad, Wang, Shunfeng, Neufurth, Meik, Lieberwirth, Ingo, Ackermann, Maximilian, Schröder, Heinz C., Wang, Xiaohong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555899/
https://ncbi.nlm.nih.gov/pubmed/33051468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73100-5
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