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Analysis of expression, epigenetic, and genetic changes of HNF1B in 130 kidney tumours

Hepatocyte nuclear factor 1 beta (HNF1B) is a transcription factor which plays a crucial role in nephronogenesis, and its germline mutations have been associated with kidney developmental disorders. However, the effects of HNF1B somatic exonic mutations and its role in the pathogenesis of kidney tum...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bártů, Michaela, Hojný, Jan, Hájková, Nikola, Michálková, Romana, Krkavcová, Eva, Hadravský, Ladislav, Kleissnerová, Lenka, Bui, Quang Hiep, Stružinská, Ivana, Němejcová, Kristýna, Čapoun, Otakar, Šlemendová, Monika, Dundr, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555858/
https://ncbi.nlm.nih.gov/pubmed/33051485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74059-z
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