Identification of novel HNF1B mRNA splicing variants and their qualitative and semi-quantitative profile in selected healthy and tumour tissues

Hepatocyte nuclear factor-1-beta (HNF1B) is a transcription factor crucial for the development of several tissues, and a promising biomarker of certain solid tumours. Thus far, two HNF1B alternative splicing variants (ASVs) have been described, however, the complete spectrum, prevalence and role of...

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Publicado en:Sci Rep
Autores principales: Hojny, Jan, Bartu, Michaela, Krkavcova, Eva, Nemejcova, Kristyna, Sevcik, Jan, Cibula, David, Fryba, Vladimir, Plincelnerova, Lenka, Dundr, Pavel, Struzinska, Ivana
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181708/
https://ncbi.nlm.nih.gov/pubmed/32332782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63733-x
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