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An Update on CARD Only Proteins (COPs) and PYD Only Proteins (POPs) as Inflammasome Regulators

Inflammasomes are protein scaffolds required for the activation of caspase-1 and the subsequent release of interleukin (IL)-1β, IL-18, and danger signals, as well as the induction of pyroptotic cell death to restore homeostasis following infection and sterile tissue damage. However, excessive inflam...

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Pubblicato in:Int J Mol Sci
Autori principali: Devi, Savita, Stehlik, Christian, Dorfleutner, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555848/
https://ncbi.nlm.nih.gov/pubmed/32962268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186901
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