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The Role of Smoothened in Cancer

Smoothened (SMO) belongs to the Hedgehog (HH) signaling pathway, which regulates cell growth, migration, invasion and stem cells in cancer. The HH signaling pathway includes both canonical and noncanonical pathways. The canonical HH pathway functions through major HH molecules such as HH ligands, PT...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Jeng, Kuo-Shyang, Sheen, I-Shyan, Leu, Chuen-Miin, Tseng, Ping-Hui, Chang, Chiung-Fang
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555769/
https://ncbi.nlm.nih.gov/pubmed/32962123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186863
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