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miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis

MicroRNA-29a (miR-29a) has been shown to ameliorate hepatocellular damage, such as in the context of non-alcoholic fatty liver disease (NAFLD), steatohepatitis (NASH), and cholestatic injury. However, the mechanism mediating the hepatoprotective effect of miR-29a in diet-induced NASH remains elusive...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yang, Ya-Ling, Wang, Pei-Wen, Wang, Feng-Sheng, Lin, Hung-Yu, Huang, Ying-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555728/
https://ncbi.nlm.nih.gov/pubmed/32961796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186884
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