Polyfunctional Fc Dependent Activity of Antibodies to Native Trimeric Envelope in HIV Elite Controllers

Antibody dependent (AD) functions such as AD cellular cytotoxicity (ADCC) were associated with lower viral load (VL) in untreated HIV progressors and protection from HIV infection in the modestly protective RV144 HIV vaccine trial. Target cells used to measure ADCC, AD complement deposition (ADCD),...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Kant, Sanket, Zhang, Ningyu, Barbé, Alexandre, Routy, Jean-Pierre, Tremblay, Cécile, Thomas, Réjean, Szabo, Jason, Côté, Pierre, Trottier, Benoit, LeBlanc, Roger, Rouleau, Danielle, Harris, Marianne, Dupuy, Franck P., Bernard, Nicole F.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555699/
https://ncbi.nlm.nih.gov/pubmed/33101312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583820
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