Polyfunctional Fc Dependent Activity of Antibodies to Native Trimeric Envelope in HIV Elite Controllers

Antibody dependent (AD) functions such as AD cellular cytotoxicity (ADCC) were associated with lower viral load (VL) in untreated HIV progressors and protection from HIV infection in the modestly protective RV144 HIV vaccine trial. Target cells used to measure ADCC, AD complement deposition (ADCD),...

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Udgivet i:Front Immunol
Main Authors: Kant, Sanket, Zhang, Ningyu, Barbé, Alexandre, Routy, Jean-Pierre, Tremblay, Cécile, Thomas, Réjean, Szabo, Jason, Côté, Pierre, Trottier, Benoit, LeBlanc, Roger, Rouleau, Danielle, Harris, Marianne, Dupuy, Franck P., Bernard, Nicole F.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555699/
https://ncbi.nlm.nih.gov/pubmed/33101312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583820
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