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Cerebral Vasodilator Property of Poly(ADP-Ribose) Polymerase Inhibitor (PJ34) in the Neonatal and Adult Mouse Is Mediated by the Nitric Oxide Pathway
The poly(ADP-ribose) polymerase (PARP) inhibitor PJ34 has been reported to improve endothelial dysfunction in the peripheral system. We addressed the role of PJ34 on the vascular tone and vasoreactivity during development in the mouse brain. Blood flows were measured in the basilar trunk using ultra...
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Published in: | Int J Mol Sci |
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Main Authors: | , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
MDPI
2020
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7555622/ https://ncbi.nlm.nih.gov/pubmed/32911782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186569 |
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