A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma

BACKGROUND: Calcium is an essential signal transduction element that has been associated with aggressive behaviours in several cancers. Cell motility is a prerequisite for metastasis, the major cause of lung cancer death, yet its association with calcium signalling and underlying regulatory axis rem...

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Publicat a:Br J Cancer
Autors principals: Luanpitpong, Sudjit, Rodboon, Napachai, Samart, Parinya, Vinayanuwattikun, Chanida, Klamkhlai, Siwaporn, Chanvorachote, Pithi, Rojanasakul, Yon, Issaragrisil, Surapol
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555538/
https://ncbi.nlm.nih.gov/pubmed/32684624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0991-7
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