Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats

Ivermectin is a widely used antiparasitic drug with known efficacy against several single-strain RNA viruses. Recent data shows significant reduction of SARS-CoV-2 replication in vitro by ivermectin concentrations not achievable with safe doses orally. Inhaled therapy has been used with success for...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chaccour, Carlos, Abizanda, Gloria, Irigoyen-Barrio, Ángel, Casellas, Aina, Aldaz, Azucena, Martínez-Galán, Fernando, Hammann, Felix, Gil, Ana Gloria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555481/
https://ncbi.nlm.nih.gov/pubmed/33051517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74084-y
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