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Discovery of Icotinib-1,2,3-Triazole Derivatives as IDO1 Inhibitors

Tumor immunotherapy is considered to be a highlight in cancer treatment in recent years. Indoleamine 2,3-dioxygenase 1 (IDO1) is closely related to the over expression of many cancers, and is therefore a promising target for tumor immunotherapy. To search for novel IDO1-targeting therapeutic agents,...

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Publicado en:Front Pharmacol
Autores principales: Mao, Long-fei, Wang, Yu-wei, Zhao, Jie, Xu, Gui-qing, Yao, Xiao-jun, Li, Yue-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555427/
https://ncbi.nlm.nih.gov/pubmed/33101032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.579024
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