Temporal Alterations in Mitochondrial β-Oxidation and Oxidative Stress Aggravate Chronic Kidney Disease Development in 5/6 Nephrectomy Induced Renal Damage

Five-sixths nephrectomy (5/6Nx) model is widely used for studying the mechanisms involved in chronic kidney disease (CKD) progression, a kidney pathology that has increased dramatically in recent years. Mitochondrial impairment is a key mechanism that aggravates CKD progression; however, the informa...

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Publié dans:Int J Mol Sci
Auteurs principaux: Aparicio-Trejo, Omar Emiliano, Rojas-Morales, Pedro, Avila-Rojas, Sabino Hazael, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, Jiménez-Uribe, Alexis Paulina, Prieto-Carrasco, Rodrigo, Sánchez-Lozada, Laura Gabriela, Pedraza-Chaverri, José, Tapia, Edilia
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555424/
https://ncbi.nlm.nih.gov/pubmed/32899919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186512
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