The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation

Cis-dichlorodiammineplatinum II (CDDP) is a chemotherapeutic agent that induces nephrotoxicity by different mechanisms, including oxidative stress, mitochondrial dysfunction, autophagy, and endoplasmic reticulum stress. This study aimed to evaluate if the protective effects of the antioxidant alpha-...

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Bibliographic Details
Published in:Antioxidants (Basel)
Main Authors: Reyes-Fermín, Laura María, Avila-Rojas, Sabino Hazael, Aparicio-Trejo, Omar Emiliano, Tapia, Edilia, Rivero, Isabel, Pedraza-Chaverri, José
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562511/
https://ncbi.nlm.nih.gov/pubmed/31096625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8050133
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