The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation

Cis-dichlorodiammineplatinum II (CDDP) is a chemotherapeutic agent that induces nephrotoxicity by different mechanisms, including oxidative stress, mitochondrial dysfunction, autophagy, and endoplasmic reticulum stress. This study aimed to evaluate if the protective effects of the antioxidant alpha-...

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Publicat a:Antioxidants (Basel)
Autors principals: Reyes-Fermín, Laura María, Avila-Rojas, Sabino Hazael, Aparicio-Trejo, Omar Emiliano, Tapia, Edilia, Rivero, Isabel, Pedraza-Chaverri, José
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562511/
https://ncbi.nlm.nih.gov/pubmed/31096625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8050133
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