Targeting Cell Cycle in Breast Cancer: CDK4/6 Inhibitors

Deregulation of cell cycle, via cyclin D/CDK/pRb pathway, is frequently observed in breast cancer lending support to the development of drugs targeting the cell cycle control machinery, like the inhibitors of the cycline-dependent kinases (CDK) 4 and 6. Up to now, three CDK4/6 inhibitors have been a...

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Bibliographic Details
Published in:	Int J Mol Sci
Main Authors:	Piezzo, Michela, Cocco, Stefania, Caputo, Roberta, Cianniello, Daniela, Gioia, Germira Di, Lauro, Vincenzo Di, Fusco, Giuseppina, Martinelli, Claudia, Nuzzo, Francesco, Pensabene, Matilde, Laurentiis, Michelino De
Format:	Artigo
Language:	Inglês
Published:	MDPI 2020
Subjects:	Review
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7554788/ https://ncbi.nlm.nih.gov/pubmed/32899866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186479
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Targeting Cell Cycle in Breast Cancer: CDK4/6 Inhibitors

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