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The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition

A considerable number of drugs and/or their metabolites are excreted by the kidneys through glomerular filtration and active renal tubule secretion via transporter proteins. Uptake transporters in the proximal tubule are part of the solute carrier (SLC) superfamily, and include the organic cation tr...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Zazuli, Zulfan, Duin, Naut J. C. B., Jansen, Katja, Vijverberg, Susanne J. H., Maitland-van der Zee, Anke H., Masereeuw, Rosalinde
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554776/
https://ncbi.nlm.nih.gov/pubmed/32927790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186627
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