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The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition

A considerable number of drugs and/or their metabolites are excreted by the kidneys through glomerular filtration and active renal tubule secretion via transporter proteins. Uptake transporters in the proximal tubule are part of the solute carrier (SLC) superfamily, and include the organic cation tr...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zazuli, Zulfan, Duin, Naut J. C. B., Jansen, Katja, Vijverberg, Susanne J. H., Maitland-van der Zee, Anke H., Masereeuw, Rosalinde
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554776/
https://ncbi.nlm.nih.gov/pubmed/32927790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186627
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