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The Reversible Non-covalent Aggregation Into Fibers of PGLa and Magainin 2 Preserves Their Antimicrobial Activity and Synergism

Magainin 2 and PGLa are antimicrobial peptides found together in frog skin secretions. When added as a mixture they show an order of magnitude increase in antibacterial activity and in model membrane permeation assays. Here we demonstrate that both peptides can form fibers with beta-sheet/turn signa...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Infect Microbiol
Asıl Yazarlar: Juhl, Dennis Wilkens, Glattard, Elise, Lointier, Morane, Bampilis, Panos, Bechinger, Burkhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554302/
https://ncbi.nlm.nih.gov/pubmed/33102247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.526459
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