Exosomes Represent an Immune Suppressive T Cell Checkpoint in Human Chronic Inflammatory Microenvironments.

BACKGROUND: T cells present in chronic inflammatory tissues such as nasal polyps (from chronic rhinosinusitis patients) have been demonstrated to be hypo-responsive to activation via the TCR, similar to tumor-specific T cells in multiple different human tumor microenvironments. While immunosuppressi...

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Veröffentlicht in:Immunol Invest
Hauptverfasser: Shenoy, Gautam N, Bhatta, Maulasri, Loyall, Jenni L, Kelleher, Raymond J, Bernstein, Joel M, Bankert, Richard B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554261/
https://ncbi.nlm.nih.gov/pubmed/32299258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08820139.2020.1748047
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