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Memory T Cells in the Chronic Inflammatory Microenvironment of Nasal Polyposis are Hyporesponsive to Signaling Through the T Cell Receptor

A majority of T cells from chronic inflammatory tissues derived from patients with nasal polyposis were found to express an effector memory phenotype. We report here that these memory T cells failed to activate NF-κB in response to TCR stimulation but responded normally when the proximal TCR signali...

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Detalhes bibliográficos
Main Authors: Lehman, Heather K., Simpson-Abelson, Michelle R., Conway, Thomas F., Kelleher, Raymond J., Bernstein, Joel M., Bankert, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346897/
https://ncbi.nlm.nih.gov/pubmed/22310933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-012-0313-8
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