Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope

Influenza virus neuraminidase (NA) contains a universally conserved epitope (NAe, NA(222–230)). However, no studies have reported vaccines targeting this NA conserved epitope and inducing antibodies recognizing NAe. The extracellular domain of M2 (M2e) is considered as an attractive target for a uni...

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Pubblicato in:Virology
Autori principali: Kim, Ki-Hye, Jung, Yu-Jin, Lee, Youri, Park, Bo Ryoung, Oh, Judy, Lee, Yu-Na, Kim, Min-Chul, Jeeva, Subbiah, Kang, Sang-Moo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554235/
https://ncbi.nlm.nih.gov/pubmed/32882637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2020.08.003
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