Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells

Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer metastasis. Its acting on phospholipid hydroperoxides and its phospholipase-A2 activity are unique among the peroxiredoxin family and add complexity to its action mechanisms. As a first step towards the study of PRDX6 invo...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: López-Grueso, María José, Lagal, Daniel José, García-Jiménez, Álvaro Fernando, Tarradas, Rosa María, Carmona-Hidalgo, Beatriz, Peinado, José, Requejo-Aguilar, Raquel, Bárcena, José Antonio, Padilla, Carmen Alicia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554216/
https://ncbi.nlm.nih.gov/pubmed/33035814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101737
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