PERK controls bone homeostasis through the regulation of osteoclast differentiation and function

Osteoclasts are multinucleated giant cells with the ability to degrade bone tissue, and are closely related to abnormal bone metabolic diseases. Endoplasmic reticulum (ER) is an organelle responsible for protein modification, quality control, and transportation. The accumulation of unfolded or misfo...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Guo, Jiachao, Ren, Ranyue, Sun, Kai, Yao, Xudong, Lin, Jiamin, Wang, Genchun, Guo, Zhou, Xu, Tao, Guo, Fengjing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554039/
https://ncbi.nlm.nih.gov/pubmed/33051453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03046-z
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