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PERK controls bone homeostasis through the regulation of osteoclast differentiation and function

Osteoclasts are multinucleated giant cells with the ability to degrade bone tissue, and are closely related to abnormal bone metabolic diseases. Endoplasmic reticulum (ER) is an organelle responsible for protein modification, quality control, and transportation. The accumulation of unfolded or misfo...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Guo, Jiachao, Ren, Ranyue, Sun, Kai, Yao, Xudong, Lin, Jiamin, Wang, Genchun, Guo, Zhou, Xu, Tao, Guo, Fengjing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554039/
https://ncbi.nlm.nih.gov/pubmed/33051453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03046-z
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