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PERK controls bone homeostasis through the regulation of osteoclast differentiation and function
Osteoclasts are multinucleated giant cells with the ability to degrade bone tissue, and are closely related to abnormal bone metabolic diseases. Endoplasmic reticulum (ER) is an organelle responsible for protein modification, quality control, and transportation. The accumulation of unfolded or misfo...
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| Опубликовано в: : | Cell Death Dis |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7554039/ https://ncbi.nlm.nih.gov/pubmed/33051453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03046-z |
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