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PERK controls bone homeostasis through the regulation of osteoclast differentiation and function

Osteoclasts are multinucleated giant cells with the ability to degrade bone tissue, and are closely related to abnormal bone metabolic diseases. Endoplasmic reticulum (ER) is an organelle responsible for protein modification, quality control, and transportation. The accumulation of unfolded or misfo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Guo, Jiachao, Ren, Ranyue, Sun, Kai, Yao, Xudong, Lin, Jiamin, Wang, Genchun, Guo, Zhou, Xu, Tao, Guo, Fengjing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554039/
https://ncbi.nlm.nih.gov/pubmed/33051453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03046-z
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