Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets

Parasites from the genus Plasmodium are the causative agents of malaria. The mobility, infectivity, and ultimately pathogenesis of Plasmodium falciparum rely on a macromolecular complex, called the glideosome. At the core of the glideosome is an essential and divergent Myosin A motor (PfMyoA), a fir...

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Pubblicato in:eLife
Autori principali: Moussaoui, Dihia, Robblee, James P, Auguin, Daniel, Krementsova, Elena B, Haase, Silvia, Blake, Thomas CA, Baum, Jake, Robert-Paganin, Julien, Trybus, Kathleen M, Houdusse, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Microbiology and Infectious Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553781/
https://ncbi.nlm.nih.gov/pubmed/33046215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60581
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