Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

The induction of an interferon-mediated response is the first line of defense against pathogens such as viruses. Yet, the dynamics and extent of interferon alpha (IFNα)-induced antiviral genes vary remarkably and comprise three expression clusters: early, intermediate and late. By mathematical model...

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Publicat a:PLoS Pathog
Autors principals: Robichon, Katharina, Maiwald, Tim, Schilling, Marcel, Schneider, Annette, Willemsen, Joschka, Salopiata, Florian, Teusel, Melissa, Kreutz, Clemens, Ehlting, Christian, Huang, Jun, Chakraborty, Sajib, Huang, Xiaoyun, Damm, Georg, Seehofer, Daniel, Lang, Philipp A., Bode, Johannes G., Binder, Marco, Bartenschlager, Ralf, Timmer, Jens, Klingmüller, Ursula
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553310/
https://ncbi.nlm.nih.gov/pubmed/33002089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008461
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