A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is an aggressive cancer related to asbestos exposure. Early diagnosis is challenging due to generic symptoms and a lack of biomarkers. We previously demonstrated that mesothelial precursor cells (MPC) characterized by mesothelin (MSLN)+CD90+CD34+ coul...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Duong, Bill T.V., Wu, Licun, Green, Brenda J., Bavaghar-Zaeimi, Fatemeh, Wang, Zongjie, Labib, Mahmoud, Zhou, Yuxiao, Cantu, Fernando J.P., Jeganathan, Thurgaa, Popescu, Sandra, Pantea, Jennifer, de Perrot, Marc, Kelley, Shana O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553233/
https://ncbi.nlm.nih.gov/pubmed/33045471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103031
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