A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma

Background: Malignant pleural mesothelioma (MPM) is an aggressive cancer related to asbestos exposure. Early diagnosis is challenging due to generic symptoms and a lack of biomarkers. We previously demonstrated that mesothelial precursor cells (MPC) characterized by mesothelin (MSLN)+CD90+CD34+ coul...

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Main Authors: Bill T.V. Duong, Licun Wu, Brenda J. Green, Fatemeh Bavaghar-Zaeimi, Zongjie Wang, Mahmoud Labib, Yuxiao Zhou, Fernando J.P. Cantu, Thurgaa Jeganathan, Sandra Popescu, Jennifer Pantea, Marc de Perrot, Shana O. Kelley
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-11-01
Colecção:EBioMedicine
Assuntos:
Mesothelioma
Liquid biopsy
Mesothelial precursor cells
Diagnostic biomarker
Clinical prognosis
Molecular profiling
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396420304072
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