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Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy

Dexamethasone, a widely used corticosteroid, has recently been reported as the first drug to increase the survival chances of patients with severe COVID-19. Therapeutic agents, including dexamethasone, are mostly transported through the body by binding to serum albumin. Here, the first structure of...

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Dettagli Bibliografici
Pubblicato in:IUCrJ
Autori principali: Shabalin, Ivan G., Czub, Mateusz P., Majorek, Karolina A., Brzezinski, Dariusz, Grabowski, Marek, Cooper, David R., Panasiuk, Mateusz, Chruszcz, Maksymilian, Minor, Wladek
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553145/
https://ncbi.nlm.nih.gov/pubmed/33063792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252520012944
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