The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner

Helminth parasites are effective in biasing Th2 immunity and inducing regulatory pathways that minimize excessive inflammation within their hosts, thus allowing chronic infection to occur whilst also suppressing bystander atopic or autoimmune diseases. Multiple sclerosis (MS) is a severe autoimmune...

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Bibliographic Details
Published in:Front Immunol
Main Authors: White, Madeleine P. J., Johnston, Chris J. C., Grainger, John R., Konkel, Joanne E., O'Connor, Richard A., Anderton, Stephen M., Maizels, Rick M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552805/
https://ncbi.nlm.nih.gov/pubmed/33117327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01830
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