The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner

Helminth parasites are effective in biasing Th2 immunity and inducing regulatory pathways that minimize excessive inflammation within their hosts, thus allowing chronic infection to occur whilst also suppressing bystander atopic or autoimmune diseases. Multiple sclerosis (MS) is a severe autoimmune...

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Vydáno v:Front Immunol
Hlavní autoři: White, Madeleine P. J., Johnston, Chris J. C., Grainger, John R., Konkel, Joanne E., O'Connor, Richard A., Anderton, Stephen M., Maizels, Rick M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552805/
https://ncbi.nlm.nih.gov/pubmed/33117327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01830
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